NDA Cell, cell division and tissues previous year questions with solutions
Cell, cell division and tissues is the largest Biology chapter of the General Studies paper, about one question in thirty, two to four a sitting. Nearly every question is one fact read off a table, with statement sets since 2023. Every question UPSC has set on it since 2017, solved. Grouped by the method each needs, newest first; open a question for its answer and worked solution.
14.1 The cell: discovery, cell theory, prokaryotic and eukaryotic cells
Answer and solution
Answer: (c) Ribosome
Method. common to both cell types
Ribosomes are present in prokaryotes and eukaryotes (NS2-A54, Class 11 ch. 8). Nucleus, mitochondria and Golgi are in eukaryotes only (NS2-A41, NS2-A43).
I. All cells possess cell wall.
II. All cells have ribosomes present inside.
III. All cells have well-organized nucleus.
IV. All cells have linear DNA molecules present in them.
Which of the statements given above is/are correct?
Answer and solution
Answer: (b) II only
Method. features common to all cells
I false: animal cells have no wall (NS2-A36). II true: ribosomes occur in all cells (NS2-A54, NS2-A43 and Class 11 ch. 8). III false: prokaryotes have no organised nucleus (NS2-A41). IV false: prokaryotic DNA is circular (NS2-A53). Only II.
Answer and solution
Answer: (d) Protein – Tissue – Organ – Organism
Method. level of organisation
Protein (molecule) goes to cells, tissue, organ, organism: increasing complexity (NS3-A02, NS2-A05).
Answer and solution
Answer: (d) 1
Method. prokaryotic chromosome
Most prokaryotes have a single circular DNA molecule in the nucleoid, i.e. one chromosome (NS2-A53).
Answer and solution
Answer: (b) proteins
Method. naked bacterial DNA
Bacterial DNA is called naked because it is not wrapped around histone proteins as in eukaryotes (Class 11 Biology ch. 8; compare NS2-A53, NS2-A50).
Answer and solution
Answer: (d) Mitochondria
Method. exclusive to eukaryotes
Mitochondria are membrane-bound organelles, absent in prokaryotes (NS2-A41, NS2-A43). Cell wall (bacteria), plasma membrane and nucleic acid occur in both.
Answer and solution
Answer: (c) Nucleus
Method. prokaryote structures
Prokaryotes have no membrane-bound nucleus (NS2-A41, NS2-A43). Cell wall, ribosomes and plasma membrane are all present.
Answer and solution
Answer: (b) Nucleoid
Method. prokaryotic nuclear region
The undefined region holding the single circular DNA is the nucleoid (NS2-A53). Nucleolus is inside a nucleus; nucleosome is a DNA-histone unit.
Answer and solution
Answer: (b) Mitochondria
Method. organelle absent in prokaryotes (membrane-bound organelles)
A prokaryotic cell has no membrane-bound organelles (NS2-A41, NS2-A43). Mitochondria are membrane-bound, so absent. Cell wall, plasma membrane and ribosomes (the one organelle common to both, NS2-A54) are all present in bacteria.
Answer and solution
Answer: (b) Robert Hooke
Method. discovery of the cell
Robert Hooke saw box-like compartments in cork in 1665 and named them cells (NS2-A09). Brown found the nucleus, Leeuwenhoek saw free living cells, Virchow said all cells arise from pre-existing cells (NS2-A87).
14.2 Plasma membrane, cell wall and transport across the membrane
Answer and solution
Answer: (d) They are composed of phospholipids, proteins and cholesterol (lipid).
Method. membrane composition
The membrane is a lipid bilayer with proteins; in animal cells cholesterol is also part of it (NS2-A26, NS2-A27; cholesterol from Class 11 ch. 8). 'Only' in (a) to (c) makes them wrong.
1. Bacterial cell wall is made of peptidoglycan.
2. Fungal cell wall is made of cellulose.
3. Animals lack cell wall and have extracellular matrix made up of sugar and proteins.
Select the correct answer using the code given below:
Answer and solution
Answer: (c) 1 and 3 only
Method. cell wall composition
1 true: bacterial wall is peptidoglycan (Class 11 ch. 8). 2 false: fungal walls are chitin, not cellulose (NS2-A37 says fungi have a wall; chitin from Class 11 ch. 2/8). 3 true: animal cells have no wall (NS2-A36) and an extracellular matrix of sugars and proteins.
Answer and solution
Answer: (a) Cell wall
Method. universal cell components
Every cell has a plasma membrane, cytoplasm and genetic material (NS2-A38, NS2-A18). The cell wall is absent in animal cells (NS2-A36), so it is not always present.
Answer and solution
Answer: (b) the cells were plasmolysed.
Method. plasmolysis
In a hypertonic solution a plant cell loses water, the cell membrane pulls away from the wall, and the cell is plasmolysed (NS2-A35, NS2-A24).
Answer and solution
Answer: (b) Animal cells have only cell membrane not cell wall, but plant cells have both.
Method. cell membrane and wall
Every cell has a plasma membrane; the cell wall lies outside it in plants (and fungi, bacteria) but is absent in animal cells (NS2-A30, NS2-A33, NS2-A36). So animal cells have the membrane only, plant cells have both.
Answer and solution
Answer: (a) Cell will lose water
Method. osmosis in animal cell
A medium with lower water concentration is hypertonic. The cell loses water and shrinks (NS2-A24, NS2-A25, NS2-A36).
Answer and solution
Answer: (d) The RBC will lyse.
Method. effect of detergent on RBC membrane
Detergent dissolves the lipid bilayer (NS2-A27), so the membrane breaks down and the RBC lyses. Swelling and bursting (c) is the osmotic result in a hypotonic solution (NS2-A24, NS2-A25), not the action of a detergent; (a) and (b) are wrong in kind.
Answer and solution
Answer: (c) Osmosis
Method. definition of osmosis
Osmosis is net movement of water across a selectively permeable membrane from a dilute solution (more water) to a concentrated one (NS2-A21, NS2-A22). Diffusion is of particles in general, without the membrane condition.
14.3 Cell organelles and their functions
Answer and solution
Answer: (b) Mitochondria and Chloroplast
Method. organelles with DNA and ribosomes
Mitochondria and chloroplasts both have their own DNA and ribosomes (NS2-A68). The other pairs lack one or both.
Answer and solution
No correct option. This question is defective as printed in UPSC's paper.
Method. lysosome statement that is not correct
(a) and (c) hold (NS2-A60). (b) is false: lysosomal enzymes digest organic macromolecules, not inorganic materials. (d) is also false: lysosomes digest foreign material that has entered, they do not stop its entry (NS2-A60).
Two options are not correct, (b) 'break down all inorganic materials' and (d) 'stop entry of foreign materials'; the question asks for the single incorrect statement. Repair: drop one of them; (b) is the likelier intended key, yielding option b.
Answer and solution
Answer: (c) Mitochondria and plastids
Method. organelles with own genetic material
Mitochondria and plastids have their own DNA (NS2-A68). ER, lysosomes and Golgi have none.
Answer and solution
Answer: (c) Mitochondria and Chloroplast
Method. organelles with own DNA
Mitochondria and chloroplasts contain their own DNA (NS2-A68). The nucleus is not paired correctly in (a); ER, Golgi, ribosomes and vacuoles have no DNA.
Answer and solution
Answer: (c) lysosomes
Method. digestive enzymes
Lysosomes are enzyme-filled sacs that digest proteins, carbohydrates and fats (NS2-A60). Ribosomes make proteins; mitochondria make ATP.
Answer and solution
Answer: (b) Leucoplast
Method. storage plastid
Leucoplasts are colourless and store starch, oils or proteins (NS2-A70). Chloroplasts make food, chromoplasts carry pigments (NS2-A69).
Answer and solution
Answer: (d) Vacuoles are absent in animal cells.
Method. vacuoles statement set
Vacuoles are present in animal cells though small, for temporary storage (NS2-A72), so (d) is not correct. (a), (b) hold from NS2-A71, NS2-A72; (c) food vacuoles in Amoeba are standard Class 11 content.
Answer and solution
Answer: (a) Smooth endoplasmic reticulum
Method. lipid synthesis organelle
Smooth ER synthesises and stores fats and hormones (NS2-A56). Golgi modifies and packs; lysosomes digest; mitochondria release energy.
Answer and solution
Answer: (d) Endoplasmic reticulum.
Method. transport inside the cell
The endoplasmic reticulum is a network continuous with the nuclear envelope, serving synthesis and transport of proteins and lipids within the cell (NS2-A55). Ribosomes synthesise protein; lysosomes digest.
Answer and solution
Answer: (c) Inner membrane.
Method. site of ATP synthesis in mitochondria
The inner membrane, folded into cristae, carries the electron transport chain and ATP synthase, where most ATP is formed (NS2-A62, NS2-A63; Class 11 Biology, Respiration in Plants). The matrix runs the Krebs cycle and yields little ATP directly.
Answer and solution
Answer: (b) Vacuole
Method. contractile vacuole
In unicellular organisms such as Amoeba, vacuoles expel excess water and wastes (NS2-A71, NS2-A72; Class 9 NCERT earlier edition, Class 11 ch. 8). Lysosomes digest; Golgi packages; ER transports.
Answer and solution
Answer: (b) Proteins
Method. semi-autonomous organelle
Mitochondria have their own DNA and ribosomes and so make some of their own proteins (NS2-A68). They cannot make a nucleus or chloroplasts; digestive enzymes are lysosomal.
Answer and solution
Answer: (d) Plasma Membrane
Method. organelle without nucleic acid
Nucleolus holds rRNA genes and rRNA, chloroplast has DNA (NS2-A68), ribosomes are made of rRNA (NS2-A54; Class 11 ch. 8). The plasma membrane is lipid and protein only (NS2-A26), no nucleic acid.
Answer and solution
Answer: (a) Ribosome
Method. organelle without its own protein-coding genes
Nucleus, mitochondria and chloroplast each carry DNA with protein-coding genes (NS2-A49, NS2-A68). A ribosome has only rRNA and proteins and carries no gene that codes for a protein (Class 11 Biology ch. 8).
Answer and solution
Answer: (c) Lysosome
Method. hydrolytic enzymes: lysosome
Lysosomes are single membrane sacs full of digestive enzymes that break down proteins, carbohydrates and fats (NS2-A60).
Answer and solution
Answer: (a) Mitochondria, nucleus, chloroplast
Method. organelles with DNA
Mitochondria and chloroplasts have their own DNA and ribosomes (NS2-A68); the nucleus holds chromosomal DNA (NS2-A49). Golgi bodies, plasma membrane and ribosomes carry no DNA, which excludes (b), (c), (d).
Answer and solution
Answer: (d) detoxification of toxic substances
Method. additional function of SER
NS2-A56 gives SER synthesis and storage of fats and hormones; the further function taught beyond the main lipid role is detoxification of poisons and drugs, notably in liver cells (Class 9 NCERT, earlier edition, ch. 5; Class 11 Biology ch. 8 gives lipid synthesis as the main SER role). Protein synthesis belongs to the rough ER (NS2-A56).
14.4 Nucleus, chromosomes and cell division
1. DNA replication takes place when chromatin is opened up.
2. Chromatin organises itself into rod-shaped chromosomes before cell division.
3. Both prokaryotes and eukaryotes have the same process for cell division.
Which of the statements given above is/are correct?
Answer and solution
Answer: (b) 1 and 2 only
Method. chromatin, chromosomes and division
1 true: DNA is replicated when chromatin is uncoiled (NS2-A50). 2 true: chromatin organises into rod-shaped chromosomes before division (NS2-A49, NS2-A50). 3 false: eukaryotes divide by mitosis or meiosis, prokaryotes by binary fission (Class 11 ch. 10).
14.5 Energy in the cell: respiration, ATP and biomolecules
Answer and solution
Answer: (b) Pyruvate
Method. lactic acid in muscle
In oxygen shortage during hard exercise, pyruvate from glucose breakdown is converted to lactic acid in muscle (Class 10 Science, Life Processes). Ethanol is the yeast route.
Answer and solution
Answer: (a) Primary structure
Method. protein structure
A linear chain of amino acids joined by peptide bonds is the primary structure (Class 11 Biology ch. 9, Biomolecules). Secondary adds helices and sheets.
Answer and solution
Answer: (b) ATP
Method. energy currency
ATP is the energy currency of the cell (NS2-A63). ADP and AMP are its lower forms; NAD is a carrier.
Answer and solution
Answer: (a) ATP + CO2 + Ethanol
Method. alcoholic fermentation
Yeast starved of oxygen ferments glucose to ethanol and CO2 with a little ATP (Class 10 Science, Life Processes). Lactic acid (c) is the muscle route; O2 is not a product.
Answer and solution
Answer: (a) pyruvate and energy
Method. glycolysis
Glucose is broken down in the cytoplasm to pyruvate with release of a little energy (ATP); no CO2 at this stage (Class 10 Science, Life Processes, respiration; Class 11 ch. 14). CO2 comes later in mitochondria or in fermentation.
14.6 Plant tissues
I. Companion cells
II. Sieve tubes
III. Tracheids
IV. Vessels
Select the answer using the code given below:
Answer and solution
Answer: (a) I, II, III and IV
Method. complex permanent tissue
Xylem and phloem are the complex permanent tissues (NS3-A40). Tracheids and vessels belong to xylem (NS3-A42); sieve tubes and companion cells belong to phloem (NS3-A43, NS3-A44). All four.
Answer and solution
Answer: (c) Sclerenchyma
Method. dead plant cells
Sclerenchyma is mostly dead, with thick lignified walls and no protoplast at maturity (NS3-A38). Collenchyma, parenchyma and xylem parenchyma are living (NS3-A36, NS3-A37, NS3-A42).
Answer and solution
Answer: (a) Lateral meristem
Method. cambium
Cambium is the ring of dividing cells giving increase in girth, the lateral meristem (NS3-A20).
Answer and solution
Answer: (a) Parenchyma
Method. aerenchyma
In aquatic plants specialised parenchyma forms air spaces that help them float (NS3-A36).
Answer and solution
Answer: (b) Parenchyma
Method. basic packing tissue
Parenchyma is the thin-walled, living, loosely packed basic tissue, present also as xylem parenchyma and phloem parenchyma (NS3-A36, NS3-A42, NS3-A44). Vessels are not a packing tissue.
Answer and solution
Answer: (b) lateral meristem only.
Method. increase in girth
Girth increases by division of the ring of lateral meristem (cambium) (NS3-A20). Apical meristem gives length (NS3-A17); intercalary gives growth at internodes (NS3-A23).
Answer and solution
Answer: (a) Cell differentiation.
Method. differentiation
Meristematic tissue becomes permanent tissue by differentiation (NS3-A28). Division only makes more cells; it does not specialise them.
Answer and solution
Answer: (d) Sclerenchyma
Method. dead plant tissue
Sclerenchyma has thick lignified walls and most of its cells are dead (NS3-A38). Epidermis, parenchyma and collenchyma are living (NS3-A31, NS3-A36, NS3-A37).
Answer and solution
Answer: (a) Xylem consists of tracheids, vessels, xylem parenchyma and xylem fibres.
Method. xylem components
Xylem has tracheids, vessels, xylem parenchyma and xylem fibres (NS3-A41, NS3-A42). (b) flexibility is collenchyma (NS3-A37); (c) parenchyma has intercellular spaces (NS3-A36); (d) lists phloem parts (NS3-A43).
Answer and solution
Answer: (c) Pericycle
Method. non-conducting tissue
Tracheids and sieve tubes conduct water and food (NS3-A41, NS3-A43); fibres are listed as parts of xylem and phloem (NS3-A42, NS3-A44). Pericycle is a layer of ground tissue just inside the endodermis and is not a conducting element (standard plant anatomy, Class 11 Biology ch. 6).
Shortcut. Fibres only support, but are components of the conducting tissues; pericycle is not.
Answer and solution
Answer: (d) Growth occurs in plants due to division of cells of these tissues
Method. function of meristematic tissue
Meristematic tissue is actively dividing; its division adds cells and causes growth (NS3-A12, NS3-A27). (a) dead wood is sclerenchyma/xylem, (b) thickened-wall flexibility is collenchyma (NS3-A37), (c) meristems are at tips, in the cambium ring and at internodes, not only in bark.
14.7 Animal tissues
Answer and solution
Answer: (a) Cardiac muscle
Method. not a connective tissue
Cartilage, blood and bone are connective tissues (NS3-A56, NS3-A66). Cardiac muscle is muscle tissue (NS3-A70).
Answer and solution
Answer: (b) Ligaments
Method. ligament
Ligaments connect bone to bone; tendons connect muscle to bone (NS3-A67).
1. Monocyte
2. Chondrocyte
3. Basophil
4. Lymphocyte
How many of the above belong to animal cell types?
Answer and solution
Answer: (d) 4
Method. animal cell types
Monocytes, basophils and lymphocytes are white blood cells (NS3-A60); chondrocytes are cartilage cells (NS3-A66, Class 11 ch. 8). All four are animal cells, so the count is 4.
Answer and solution
Answer: (a) Oesophagus.
Method. squamous epithelium location
Stratified squamous epithelium of flat cells protects the lining of skin, mouth and oesophagus (NS3-A53). Small intestine is columnar absorptive (NS3-A55) and salivary ducts are cuboidal/columnar.
Answer and solution
Answer: (d) Connective tissue
Method. blood as a tissue type
Blood has cells in a fluid matrix (plasma) and is a connective tissue (NS3-A56, NS3-A57).
Answer and solution
Answer: (b) Muscle tissue
Method. contractile proteins = muscle tissue
Muscle fibres contract through actin and myosin; muscle tissue is the contractile tissue (NS3-A68 to NS3-A70, standard Class 11 content for the proteins). Nerve, bone and blood do not shorten.
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